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Charles
N. Rotimi
Howard
University,
College of Medicine
National
Human Genome
Center
2216
6th
Street, NW,
Suite 206, Washington,
DC 20059
Phone:
202-806-5419
Fax: 202-265-2254
Email:
crotimi@howard.edu
University
of Benin, Nigeria B.S. 1979 Biochemistry
University
of Mississippi
M.S.
1983 Health
Care Administration.
University
of Alabama at
Birmingham
MPH 1988 Epidemiology
University
of Alabama at
Birmingham Ph.D. 1991 Epidemiology
RESEARCH AND
EDUCATIONAL
EXPERIENCE:
1992-1998 Assistant
Professor,
Department of
Preventive Medicine
& Epidemiology,
Loyola University
1996-
Present
Grant Reviewer:
NIH
1995-
Present Manuscript
Reviewer: Several
Professional
journals (e.g.,
American Journal
of Human Genetics,
Hypertension
and International
Journal of Obesity,
etc)
1998-
1999
Associate
Professor,
Department of
Preventive Medicine,
Loyola University
Chicago
1999-
Present
Director,
Genetic
Epidemiology,
Nation Human
Genome Center,
Howard University.
2001-
Present
Member
Adi-Map: An
Obesity gene
mapping collaborative
project. NIDDK/NIH
2000-
Present
Member
Genetics Committee:
Jackson
Heart Study
(NHLBI/NIH).
2001
Co-Chair
American Diabetes
Association:
61st
Scientific Session
in Philadelphia,
PA.
2001-
Present
Member
Framingham Monitoring
Board
2001-
Present
Consultant
Clinical Research
Center: Morehouse
School of Medicine,
Atlanta,
2001-
Present
Member
of Advisory
Committee: Haplotype
Map Project
(NHGRI/NIH)
2002-
Present
Member
of NICHD Monitoring
Board: National
Institute of
Child Health
2004-
Present President,
African
Society of Human
Genetics
2003-
Present Professor,
College
of Medicine,
Howard University.
2004-
Present Acting
Director, National
Human Genome
Center at Howard
University.
PUBLISHED PAPERS
(selected from
a list of 84)
1. Rotimi
CN, Cooper RS,
Sundarum CB,
Cao G. Familial
Aggregation
of cardiovascular
diseases in
African-American
Pedigrees: Genetic
Epidemiology
1994;11:397-407.
2. Rotimi
CN, Morrison
L, Cooper R,
et al.
Angiotensinogen
gene in human
hypertension:
Lack of an association
of the M235T
allele among
African Americans.
Hypertension,
1994;24:591-594.
3. Cooper
RS, Rotimi CN:
Hypertension
in populations
of West African
origin: Is there
a genetic predisposition?
J Hypertension
1994; 12:215-227
4. Rotimi
CN, Cooper RS,
Ataman SL, et
al. Distribution
of Anthropometric
variables and
the prevalence
of obesity in
populations
of West African
origin. Obesity
Research 1995;
3(suppl 2):
95s-105s.
5. Rotimi
CN, Cooper RS:
Familial resemblance
of anthropometric
measurements
and relative
fat distribution
among African
Americans.
Int
J Obes 1995;
19:875-880.
6. Rotimi
CN, Puras A,
Cooper RS, et
al.
Polymorphisms
of Renin-Angiotensin
Genes Among
Nigerians, Jamaicans
and African
Americans.
Hypertension
1996; 27:558-563
7. Forrester
T, McFarlane-Anderson
N, Bennet F,
Wilks R, Puras
A, Cooper R,
Rotimi C, et
al. Angiotensinogen
and blood pressure
among blacks:
findings from
a community
survey in Jamaica.
J Hypertension
1996; 14:315-321.
8. Cooper
R, Rotimi C,
Kaufman JS,
et al.
Prevalence
of NIDDM among
populations
of the African
Diaspora. Diabetes
Care 1997; 20:343-348.
14. Cooper
R, Rotimi C,
Ataman S, et.
al., The prevalence
of hypertension
in seven populations
of West African
Origin. Am J
Public Health.
1997; 87:160-168.
15 Rotimi
CN, Cooper RS,
Marcovina SM,
et al. Serum
distribution
of lipoprotein(a)
in African Americans
and Nigerians:
potential evidence
for a genotype-environmental
effect.
Genetic Epidemiology
1997; 14(2):
152-168.
16. Rotimi
C, Luke A, Li
Z, Compton JA,
et al. Familial
aggregation
of plasma leptin
levels in African-American
families.
Genetic Epidemiol
1997; 14:255-263.
17. Rotimi
CN, Cooper RS,
Ogunbiyi O,
et al.
Hypertension,
Serum Angiotensinogen
and Molecular
Variants of
the Angiotensinogen
Gene among Nigerians.
Circulation
1997; 95:2348-2350.
18. Forrester
T, McFarlane-Anderson
N, Bennett FI,
Wilks R, Cooper
R, Rotimi C,
et al. The I/D
polymorphism
of the ACE gene,
serum ACE activity
and blood pressure
in Jamaicans.
Am J Hypertens
1997;10
19. Luke
AH, Rotimi CN,
Cooper RS, et
al. Leptin and
body composition
of Nigerians,
Jamaicans, and
US blacks.
Am J Clin Nutr
1998:67:391-6.
20. Cooper
R, Rotimi C,
Kaufman J, Muna
W, Osotimehin
B. Hypertension
treatment and
control in sub-Saharan
Africa: the
epidemiological
basis for policy.
BMJ 1998;316.614-617.
21. Cooper
RS, Rotimi CN,
Ward R. The
puzzle of hypertension
in African-Americans.
Scientific American
1999;56-62
22. Rotimi
CN, Comuzzie
AG, Lowe WL,
Luke A, Blangero
J, Copper RS.
The QTL on chromosome
2 for serum
leptin levels
is confirmed
in African Americans.
Diabetes, 1999;
18:643-644.
23. Rotimi
CN, Cooper RS,
Cao G, et al.
Maximum likelihood
generalized
heritability
estimates for
systolic and
diastolic blood
pressure among
Nigerian Families.
Hypertension,1999;
33:874-878.
24. Rotimi
C, Cooper R,
Okosun I, et
al.
Prevalence
of diabetes
and impaired
glucose tolerance
in Nigerians,
Jamaicans, and
U.S. blacks.
Ethnicity and
Disease 1999;
9:190-200.
25. Okosun
I, Cooper R,
Prewitt ET,
Rotimi C. The
relation of
central adiposity
to components
of the insulin
resistance syndrome
in a biracial
US population
sample. Ethnicity
and Disease
1999;9:218-229
26. Chang
WK, Luke A,
Rotimi CN, et
al. Genetic
and Physiologic
analysis of
the role of
uncoupling protein
3 in human energy
hemostasis.
Diabetes 1999;
48:1890-1895
27. Chung
WK, Luke A,
Cooper RS, Rotimi
C, et al: The
Long isoform
uncoupling protein-3
(UCP3L) in human
energy homeostasis.
Int J Obes Relat
Metab Disord
1999; 6:S49-50
28. Wilks
R, Rotimi C,
Bennett F, et
al. Diabetes
in the Caribbean:
results of a
population survey
from Spanish
Town, Jamaica.
Diabetes
Medicine 1999:10:875-83
29. Cooper
RS, Guo X, Rotimi
CN, et al.
Heritability
of angiotensin-converting
enzyme and angiotensinogen:
A comparison
of US blacks
and Nigerians.
Hypertension
2000;35:1141-1147
30. Schork
NJ, Chakravarti
A, Theil B,
et al. Lack
association
between a biallelic
polymorphism
in the adducin
gene and blood
pressure in
whites and African
Americans. Am
J Hypertens
2000;13:693-8
31. Luke
A, Rotimi CN,
Adeyemo A et
al.
Comparability
of resting energy
expenditure
in Nigerians
and US Blacks.
Obes
Res. 2000;8:351-359
32. Rotimi
C, Dunston G,
Berg K, et al.
In
Search of Susceptibility
Genes for Type
2 Diabetes In
West Africa:
The design and
results of the
first phase
of the AADM
Study. Ann of
Epidemiol 2001;
11:51-58.
33. Hu
YJ, Korotkov
KV, Mehta R,
et al. Ethnic
distribution
and functional
consequences
of nucleotide
polymorphisms
in the 3'-untranslated
region of the
human 15 kDa
selenoprotein
gene. Cancer
Res. 2001 Mar
1;61(5):2307-10.
34. Lowe
Jr WL, Rotimi
CN, Luke A,
et al. The beta
3-adrenergic
receptor gene
and obesity
in a population
sample of African
Americans. Int
J Obes Relat
Metab Disord
2001; 1:54-60
35.
Luke A,
Guo X, Adeyemo
AA, Wilks R,
Forrester T,
Lowe Jr W, Comuzzie
AG, Martin LJ,
Zhu X, Rotimi
CN, Cooper RS.
Heritability
of obesity-related
traits among
Nigerians, Jamaicans
and US black
people. Int
J Obes Relat
Metab Disord.
2001 Jul;25(7):1034-41
36. Marshall
PA, Rotimi C.
Ethical challenges
in community-based
research.
Am
J Med Sci 2001
Nov;322(5):241-5
37. Adeyemo
AA, Prewitt
TE, Luke A,
Omotade OO,
Rotimi CN, et
al.The feasibility
of implementing
a dietary sodium
reduction intervention
among free-living
normotensive
individuals
in south west
Nigeria. Ethn
Dis 2002;12:207-12
38. Gabriel
S, Schaffner
S, Nguyen H,
Moore J, Roy
J, Blumenstiel
B, DeFelice
M, Lochner A,
Faggart M, Liu-Cordero
S, Rotimi C,
et al.The Structure
of Haplotype
Blocks in the
Human Genome.
Science 20021;
296: 225
39. Adeyemo
AA, Omotade
OO, Rotimi CN,
et al.
Heritability
of blood pressure
in Nigerian
families. J
Hypertens 2002
May;20(5):859-63
40. Luke
A, Durazo-Arvizu
RA, Rotimi CN,
et al.
Activity
energy expenditure
and adiposity
among black
adults in Nigeria
and the United
States.
Am J Clin Nutr.
2002 Jun;75(6):1045-50.
41. Cooper
RS, Luke A,
Zhu X, Kan D,
Adeyemo A, Rotimi
C, et al.
Genome scan
among Nigerians
linking blood
pressure to
chromosomes
2, 3, and 19.
Hypertension.
2002 Nov;40(5):629-33.
42. Adeyemo
A, Luke A, Cooper
R, Wu X, Tayo
B, Zhu X, Rotimi
C, Bouzekri
N, Ward R.A
genome-wide
scan for body
mass index among
Nigerian families.
Obes Res. 2003
Feb;11(2):266-73.
43. Daniel
HI, Rotimi CN.Genetic
epidemiology
of hypertension:
an update on
the African
diaspora. Ethn
Dis. 2003 Summer;13(2
Suppl 2):S53-66.
44. Rotimi
C, Daniel H,
Zhou J, et al.Prevalence
and determinants
of diabetic
retinopathy
and cataracts
in West African
type 2 diabetes
patients. Ethn
Dis. 2003 Summer;13(2
Suppl 2):S110-7.
45. Rotimi
CN. Genetic
Ancestry Tracing
and the African
Identity: A
Double-Edged
Sword? Developing
World Bioethics
3(2) December
2003; 151-158.
46. Chen
G, Zhou J, Chen
Y, Daniel H,
Rotimi C.Genome
wide search
for blood pressure
susceptibility
loci in West
African Type
2 diabetes patients.
Ann Epidemiol.
2003 Sep; 13(8):
567-8.
47. Gibbs
RA, et al. The
International
HapMap Project.
Nature.
2003 Dec 18;
426(6968): 789-96.
48. Rotimi
CN, Chen G,
Adeyemo A et
al.
A
Genome-Wide
Search for Type
2 Diabetes Susceptibility
Genes In West
Africans: The
AADM study.
Diabetes, 2004
March;53: 838-841.
49. International
HapMap Consortium.
Integrating
ethics and science
in the International
HapMap Project.
Nat Rev Genet.
2004 Jun;5(6):467-75
50. Rotimi
CN. Inauguration
of the African
Society of Human
Genetics. Nat
Genet. 2004
Jun;36(6):544.
51. Yuan
A, Chen G, Chen
Y, Rotimi C,
Bonney GE.
Identifying
the Susceptibility
Gene(s) in a
Set of Trait-Linked
Genes Using
Genotype Data.
Genetics. 2004
167(3):1445-59.
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